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Persistent NK cell deficiency associated with pulmonary cryptococcosis

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12941_2024_Article_771.pdf (1.09 MB)

Date

2025-01-18

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Abstract

Abstract We describe pulmonary cryptococcosis in a 28-year-old previously healthy man. Exhaustive immunological investigations revealed a primary NK cell deficiency associated with a secondary impaired anti-Cryptococcus CD8 lymphocyte response and the expansion of a CD8Vβ14 + T cell clone. This case illustrates the potential role of NK cells in immunity against Cryptococcus.

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Annals of Clinical Microbiology and Antimicrobials. 2025 Jan 18;24(1):6

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https://hdl.handle.net/1880/120526

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