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Optimizing Response to Cardiac Resynchronization Therapy for Patients with Heart Failure

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atmire.migration.oldid6165
dc.contributor.advisorExner, Dr Derek V.
dc.contributor.authorManga, Sharita
dc.contributor.committeememberAllu, Selina
dc.contributor.committeememberBelenkie, Dr Israel
dc.contributor.committeememberHowarth, Dr Andrew
dc.contributor.committeememberRaj, Dr Satish
dc.contributor.committeememberWilton, Dr Stephen
dc.date.accessioned2017-11-02T18:10:51Z
dc.date.available2017-11-02T18:10:51Z
dc.date.issued2017
dc.date.submitted2017en
dc.description.abstractUp to one third of patients with heart failure, who meet the current guidelines for cardiac resynchronization therapy (CRT), do not derive a significant benefit from this device therapy. This thesis explores novel methods to optimize response to CRT, as well as investigates the physiologic mechanisms involved in benefit. Finally, surrogate markers of CRT response are compared to patient important outcomes in a systematic review to understand the relationship. The overarching conclusion is that optimizing CRT response requires individualized pre-implant, implant and post implant considerations.en_US
dc.identifier.citationManga, S. (2017). Optimizing Response to Cardiac Resynchronization Therapy for Patients with Heart Failure (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/27216en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/27216
dc.identifier.urihttp://hdl.handle.net/11023/4234
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectBiophysics--Medical
dc.subjectMedicine and Surgery
dc.subject.otherCRT
dc.subject.otherheart failure
dc.subject.otherresynchronization
dc.titleOptimizing Response to Cardiac Resynchronization Therapy for Patients with Heart Failure
dc.typemaster thesis
thesis.degree.disciplineCardiovascular & Respiratory Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue

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